Previous studies showed that epiblast cells, unlike primitive ectoderm cells, are refractory to LIF–STAT3 signalling; instead they respond to activin/basic fibroblast growth factor (bFGF) to generate ...
Activation of the TEAD transcription factor in the inner cell mass induces strong expression of pluripotency factors, which is required for epiblast formation. The expression of pluripotency factors ...
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