Chemical changes to histones, the proteins that help to pack and organize DNA inside cells, play a key role in determining what genes will be consistently activated over the course of an animal or ...

Histone modifications constitute a dynamic layer of epigenetic regulation that shapes gene expression programmes central to fungal virulence, morphogenesis and drug resistance. In pathogenic fungi ...

University of North Carolina at Chapel Hill researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...

Modification of histone tails, by acetylation, methylation or phosphorylation, affects the local chromatin structure and the transcriptional regulation of adjacent genes. Pericentric heterochromatin ...

A new study has decoded how pea plants respond to salt stress through precise epigenetic reprogramming. Researchers created the first genome-wide map of four major histone modifications—H3K4me3, ...

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

Researchers found that KAT7 promotes CMPK2-driven mitochondrial DNA release in microglia, activating inflammatory cGAS-STING ...

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...

Researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation. Researchers have determined ...