When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting ...

During replication, DNA polymerases are positioned on each strand of DNA . Using a microscope slide as an anchor, we tethered DNA to a bead and stretched it with a flow of solution. We tracked how the ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

When an SSB appears, polymerase epsilon approaches the nick before retracing its steps thanks to its exonuclease, allowing fork reversal to take place. The nick is repaired as an SSB, and replication ...