UCLA researchers have developed a lipid nanoparticle-based gene-editing approach capable of inserting an entire healthy gene into human airway cells, restoring key biological function in a laboratory ...

Researchers developed a simulation showing how lipid nanoparticles release mRNA in acidic endosomes. The study reveals how ...

A study from FAU has shown that lipid nanoparticles restructure their membrane significantly after being absorbed into a cell ...

LNPs consist of ionizable lipids, which are critical for encapsulating RNA and enabling cellular uptake. Helper lipids contribute to the structural integrity and fusion with cell membranes.

Lipid-based nanoparticles are a popular research area as a non-viral platform for delivering RNA molecules and include liposomes, lipoplexes, lipid nanoparticles and solid lipid nanoparticles. Using ...

Johns Hopkins researchers have identified minuscule particles that supercharge therapeutic cancer vaccines, which train the immune system to attack tumors. These new lipid nanoparticles—tiny ...

Liposomes and lipid nanoparticles (LNPs) are versatile drug delivery systems that allow precise control over composition, morphology, and structure, tailoring these features to meet specific ...

Therapeutics that use mRNA - like some of the COVID-19 vaccines - have enormous potential for the prevention and treatment of many diseases. These therapeutics work by shuttling mRNA 'instructions' ...

This groundbreaking development may enable treatments for inflammatory diseases such as Crohn's and colitis. Researchers at Tel Aviv University have achieved a major breakthrough in drug delivery: ...