A mum who was diagnosed with Down’s syndrome aged 23 says people “don’t believe” she has the condition. Ashley Zambelli was diagnosed with mosaic Down’s syndrome in February 2023 after undergoing ...

After decades of mystery, researchers at Gladstone Institutes identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice. SAN FRANCISCO—October 22, ...

Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that require surgery in the first months of life. For decades, scientists have ...

Researchers identified mosaicism as a possible factor influencing Alzheimer’s risk in adults with Down syndrome, offering new insights into amyloid biomarkers and their broader implications for the ...