The mechanism behind volutrauma is two-fold: one part increased alveolar-capillary permeability and one part increased transmural pressure. As alveoli become overdistended, the alveolar epithelium ...

Using a lung and diaphragm protective ventilation strategy guided by a computerized decision support tool during the acute phase of ventilation shortened the duration of weaning, a pediatric phase II ...

Low-tidal-volume lung-protective ventilation during major abdominal surgery may reduce postoperative complications, according to a multicenter, double-blind, parallel-group randomized controlled trial ...

March 27, 2012 — Reducing breath size and pressure settings for mechanical ventilators used in intensive care units can substantially improve long-term survival in patients with acute lung injury (ACI ...

OBJECTIVE To evaluate the effects of intraoperative protective ventilation on major postoperative respiratory complications and to define safe intraoperative mechanical ventilator settings that do not ...

Background: In anesthetized patients undergoing surgery, the role of lung-protective ventilation with lower tidal volumes is unclear. We performed a meta-analysis of randomized controlled trials (RCTs ...