A gene therapy for a rare type of severe combined immunodeficiency (SCID) was safe and sufficiently restored T-cell immunity in an early trial, results from a phase I/II study showed. At a single ...

Twice as many infants may be affected by severe combined immunodeficiency (SCID) than previously believed, a study has shown. The findings, published in the August 20 issue of JAMA, support the view ...

NEW ORLEANS -- A next generation genetic therapy appeared to restore the immune system of patients with "bubble boy disease," but without leading to leukemia as a side effect, researchers reported ...

Researchers headed by teams at Newcastle University, the Wellcome Sanger Institute, and the Great North Children’s Hospital have identified a single gene mutation common to 11 pediatric patients with ...

The first gene chip ever to be developed for detecting SCID (primary immunodeficiency) in newborns will be presented to researchers for the first time at the New York Academy of Sciences' and Jeffrey ...

Severe Combined Immunodeficiency (SCID) is a rare, life-threatening immunological disorder characterized due to the lack of B-lymphocyte and T-lymphocyte functioning. Sporadic (occasional) ...

An experimental gene therapy developed to treat children born with a rare immunodeficiency disease has demonstrated extraordinary efficacy according to a new long-term follow-up study published in the ...

Is there a new way to manage Severe Combined Immunodeficiency (SCID) in infants? Yes, gene therapy is a discovery for the affected babies. Ten young children born without functioning immune systems ...

Please provide your email address to receive an email when new articles are posted on . The FDA announced it has allowed marketing of the EnLite Neonatal TREC Kit, a screening test for severe combined ...

We have previously compared the repopulation ability of gene-modified baboon CD34 + cells in an autologous transplantation versus a xenotransplant model in irradiated nonobese diabetic/severe combined ...

After a decade of unsuccessful attempts to correct one form of severe combined immunodeficiency using gene therapy, success has finally been achieved in another genetic type. Whether this success is ...

The activity of their specialized white blood cells (T and B lymphocytes, and, occasionally, natural killer cells) is so low that the body lacks its primary defense response, leaving it vulnerable to ...